Article

Initial pig developmental stage influences intestinal organoid growth but not phenotype

2024-01-30

Abstract excerpt

Intestinal organoids are promising tools in the context of animal experiment reduction. Yet, a thorough characterization of the impact of the origin of intestinal stem cells (ISC) on organoid phenotype is needed to routinely use this cellular model. Our objective was to evaluate the effect of ISC donor age on the growth, morphology and cellular composition of intestinal organoids derived from pig, a valuable model...

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Literature Corpus work: 5e89a206-3c6e-5897-856b-43855122a891
DOI: 10.1101/2024.01.26.577507

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