Article

PD-1 and PD-L1 are diagnostic biomarkers and PD-L1 a promising therapeutic target in HER2-positive and triple negative normal-like feline mammary carcinoma subtypes

2020-04-27

Abstract excerpt

Tumor microenvironment has gained great relevance due to its ability to regulate distinct checkpoints mediators, orchestrating tumor progression. In order to understand the role of the PD- 1/PD-L1 axis in cats with mammary carcinoma, serum PD-1 and PD-L1 levels were compared with healthy controls and with serum CTLA-4 and TNF- α levels. PD-1 and PD-L1 expression was evaluated in TILs and cancer cells, as the pres...

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Literature Corpus work: 0013dd55-26f7-5529-a4da-8ed3238b6d42
DOI: 10.1101/2020.04.25.061655

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