Article

The caninized anti-canine PD-1 monoclonal antibody in canine oral malignant melanoma: Efficacy and exploratory biomarker analysis

2025-08-28

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Canine oral malignant melanoma (OMM) is a highly aggressive tumor with few treatment options. Because of its biological similarity to human mucosal melanoma, canine OMM represents a valuable spontaneous model for translational immunotherapy studies. Anti-PD-1 antibody therapy has shown promise in canine OMM; however, predictive biomarkers for treatment response and survival...

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Literature Corpus work: cf6e282e-a1f2-531b-adab-6e1ac44140cc
DOI: 10.1101/2025.08.26.671889

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