Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans.

Nature genetics - 1 Feb 1999

Cox N J, Frigge M, Nicolae D L, Concannon P, Hanis C L, Bell G I, Kong A

Abstract excerpt

Complex disorders such as diabetes, cardiovascular disease, asthma, hypertension and psychiatric illnesses account for a large and disproportionate share of health care costs, but remain poorly characterized with respect to aetiology. The transmission of such disorders is complex, reflecting the actions and interactions of multiple genetic and environmental factors. Genetic analyses that allow for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 15
Share to Chromosomes, Human, Pair 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Genetic Linkage

Share to Genetic Predisposition to Disease

Share to Mexican Americans

Share to Pancreatic function and diabetes

Source

Identifiers

PMID: 9988276
DOI: 10.1038/6002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans.PMID 9988276Read ↗

Linkage of type 2 diabetes on chromosome 9p24 in Mexican Americans: additional evidence from the Veterans Administration Genetic Epidemiology Study (VAGES).Semantic proximity Read ↗

Genomewide search for type 2 diabetes susceptibility genes in four American populations.Semantic proximity Read ↗

A locus on chromosome 15q26 (IDDM3) produces susceptibility to insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Fine mapping of the diabetes-susceptibility locus, IDDM4, on chromosome 11q13.Semantic proximity Read ↗

Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes.Semantic proximity Read ↗

Genome-wide linkage and admixture mapping of type 2 diabetes in African American families from the American Diabetes Association GENNID (Genetics of NIDDM) Study Cohort.Semantic proximity Read ↗

A major susceptibility locus influencing plasma triglyceride concentrations is located on chromosome 15q in Mexican Americans.Semantic proximity Read ↗

A gene conferring susceptibility to type 2 diabetes in conjunction with obesity is located on chromosome 18p11.Semantic proximity Read ↗

A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.Semantic proximity Read ↗

A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14.Semantic proximity Read ↗

Applying novel genome-wide linkage strategies to search for loci influencing type 2 diabetes and adult height in American Samoa.Semantic proximity Read ↗

Linkage disequilibrium mapping of a type 1 diabetes susceptibility gene (IDDM7) to chromosome 2q31-q33.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.