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Article

Mucosal DNA vaccine immunization against measles with a highly attenuated Shigella flexneri vector.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 1999

Fennelly G J, Khan S A, Abadi M A, Wild T F, Bloom B R

Abstract excerpt

An intranasal vaccine vector would elicit protective immunity at the respiratory mucosa, the portal of entry and the primary site for replication for measles virus (MV) and other respiratory viruses. In a murine model of pulmonary Shigella, we demonstrate here that a candidate-attenuated Shigella vaccine vector is safely tolerated in IFN-gamma deficient mice at an inoculum that is 1 million-fold higher than the...

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PMID: 9973419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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