Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of a multicomponent live, attenuated Shigella flexneri vaccine.

Pathogens and disease - 1 Jul 2016

DeLaine BreOnna C, Wu Tao, Grassel Christen L, Shimanovich Avital, Pasetti Marcela F, Levine Myron M, Barry Eileen M

Abstract excerpt

Shigella flexneri is a leading cause of diarrheal disease in children under five in developing countries. There is currently no licensed vaccine and broad spectrum protection requires coverage of multiple serotypes. The live attenuated vaccines CVD 1213 and CVD 1215 were derived from two prominent S. flexneri serotypes: S. flexneri 3a and S. flexneri 6. To provide broad-spectrum immunity, they could be combined...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Bacterial
Share to Cytotoxicity, Immunologic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dysentery, Bacillary

Share to Guinea Pigs

Share to Immunization

Share to Shigella flexneri

Share to Vaccines, Attenuated

Share to Vaccines, Synthetic

Source

Open in PubMed Open full text

Identifiers

PMID: 27106253
DOI: 10.1093/femspd/ftw034
PMCID: PMC5985478

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of a multicomponent live, attenuated Shigella flexneri vaccine.PMID 27106253Read ↗

Status of vaccine research and development for ShigellaSemantic proximity Read ↗

Live Attenuated Shigella dysenteriae Type 1 Vaccine Strains Overexpressing Shiga Toxin B SubunitSemantic proximity Read ↗

Deletion in the Shigella enterotoxin genes further attenuates Shigella flexneri 2a bearing guanine auxotrophy in a phase 1 trial of CVD 1204 and CVD 1208.Semantic proximity Read ↗

The Shigella Vaccines PipelineSemantic proximity Read ↗

A next-generation GMMA-based vaccine candidate to fight shigellosisSemantic proximity Read ↗

Frontiers in Shigella Vaccine DevelopmentSemantic proximity Read ↗

Live attenuated Shigella flexneri mutants as vaccine candidates against shigellosis and vectors for antigen delivery.Semantic proximity Read ↗

Human challenge study with a Shigella bioconjugate vaccine: Analyses of clinical efficacy and correlate of protectionSemantic proximity Read ↗

Development and administration of live Shigella vaccines.Semantic proximity Read ↗

Construction and evaluation of live attenuated vaccine strains of Shigella flexneri and Shigella dysenteriae 1.Semantic proximity Read ↗

Vaccines Against Shigella and Enterotoxigenic Escherichia coli: A summary of the 2018 VASE ConferenceSemantic proximity Read ↗

A broad spectrum Shigella vaccine based on VirG53–353 multiepitope region produced in a cell-free systemSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.