Human Th1 and Th2 lymphocytes: their role in the pathophysiology of atopy.

doi:10.1111/j.1398-9995.1992.tb00662.x

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Article

Human Th1 and Th2 lymphocytes: their role in the pathophysiology of atopy.

Allergy - 1 Oct 1992

Del Prete G

Abstract excerpt

In human beings, as in mice, two distinct patterns of cytokine secretion have been defined among CD4+ helper T-cell clones. Human type 1 helper (Th1), but not type 2 helper (Th2), cells produce interleukin-2 (IL-2), gamma-interferon (IFN-gamma), and tumor necrosis factor-beta, whereas Th2, but no...

Topics

Allergens
Cytokines
Humans
Hypersensitivity, Immediate
Immunoglobulin E
Interferon-gamma
Interleukin-4
Mast Cells
Phenotype
T-Lymphocyte Subsets
T-Lymphocytes, Helper-Inducer

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