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Article

HIV Tat/P-TEFb Interaction: A Potential Target for Novel Anti-HIV Therapies

17 Apr 2018

Abstract excerpt

Transcription is a crucial step in the life cycle of the human immunodeficiency virus type 1 (HIV 1) and is primarily involved in the maintenance of viral latency. Both viral and cellular transcription factors, including transcriptional activators, suppressor proteins and epigenetic factors, are involved in HIV transcription from the proviral DNA integrated within the host cell genome. Among them, the...

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PMID: 29673219
DOI: 10.3390/molecules23040933

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