Article
A MAGE-1-encoded HLA-A24-binding synthetic peptide induces specific anti-tumor cytotoxic T lymphocytes.
International journal of cancer - 18 Jan 1999
Fujie T, Tahara K, Tanaka F, Mori M, Takesako K, Akiyoshi T
Abstract excerpt
Although several MAGE-1 peptides have already been identified, the MAGE-1-encoded peptide presented by HLA-A24, which is the most common allele in Japanese population and is also frequently present in Caucasians, might have a wide applicability for immunotherapy using these peptides. To identify...
Topics
- Alleles
- Antibodies, Monoclonal
- Antibody Specificity
- Antigens, Neoplasm
- Cell Line
- Genetic Code
- HLA-A Antigens
- Humans
- Melanoma-Specific Antigens
- Neoplasm Proteins
- RNA, Messenger
- Reverse Transcriptase Polymerase Chain Reaction
- T-Lymphocytes, Cytotoxic
- T-Lymphocytes, Regulatory
- Tumor Cells, Cultured