Article
GRC5 and NMD3 function in translational control of gene expression and interact genetically.
Current genetics - 1 Jan 1999
Karl T, Onder K, Kodzius R, Pichová A, Wimmer H, Th r A, Hundsberger H, Löffler M, Klade T, Beyer A, Breitenbach M, Koller L
Abstract excerpt
The yeast gene, GRC5 (growth control), is a member of the highly conserved QM gene family, the human member of which has been associated with the suppression of Wilms' tumor. GRC5 encodes ribosomal protein L10, which is thought to play a regulatory role in the translational control of gene expression. A revertant screen identified four spontaneous revertants of the mutant grc5-1ts allele. Genetic and phenotypic...
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