Article
The yeast growth control gene GRC5 is highly homologous to the mammalian putative tumor suppressor gene QM.
Yeast (Chichester, England) - 1 Jan 1996
Koller H T, Klade T, Ellinger A, Breitenbach M
Abstract excerpt
We isolated the Saccharomyces cerevisiae GRC5 (growth control) gene by functional complementation in vivo of a ts (temperature sensitive) mutation. Phenotypic analysis suggested involvement of GRC5 in cell growth and proliferation. Mutant cells arrest their cell cycles after one to three cell divisions predominantly as mother cells with a large bud. In the region of the septum, a massive accumulation of cell wall...
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