The yeast growth control gene GRC5 is highly homologous to the mammalian putative tumor suppressor gene QM.

doi:10.1002/(SICI)1097-0061(199601)12:1%3C53::AID-YEA886%3E3.0.CO;2-M

Back to search

Article

The yeast growth control gene GRC5 is highly homologous to the mammalian putative tumor suppressor gene QM.

Yeast (Chichester, England) - 1 Jan 1996

Koller H T, Klade T, Ellinger A, Breitenbach M

Abstract excerpt

We isolated the Saccharomyces cerevisiae GRC5 (growth control) gene by functional complementation in vivo of a ts (temperature sensitive) mutation. Phenotypic analysis suggested involvement of GRC5 in cell growth and proliferation. Mutant cells arrest their cell cycles after one to three cell div...

Topics

Base Sequence
Cell Division
Chromosome Mapping
Cloning, Molecular
DNA, Fungal
Genes, Fungal
Genes, Tumor Suppressor
Genetic Complementation Test
Humans
Molecular Sequence Data
Mutation
Phenotype
Saccharomyces cerevisiae

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.