Article
Mitochondrial aging: open questions.
Annals of the New York Academy of Sciences - 20 Nov 1998
Beckman K B, Ames B N
Abstract excerpt
Interest in the role of mitochondria in aging has intensified in recent years. This focus on mitochondria originated in part from the free radical theory of aging, which argues that oxidative damage plays a key role in degenerative senescence. Among the numerous mechanisms known to generate oxida...
Topics
- Aging
- Animals
- Antioxidants
- DNA, Mitochondrial
- Humans
- Life Expectancy
- Longevity
- Mammals
- Mitochondria
- Mutation
- Oxidants
- Oxidative Phosphorylation