Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial aging: open questions.

Annals of the New York Academy of Sciences - 20 Nov 1998

Beckman K B, Ames B N

Abstract excerpt

Interest in the role of mitochondria in aging has intensified in recent years. This focus on mitochondria originated in part from the free radical theory of aging, which argues that oxidative damage plays a key role in degenerative senescence. Among the numerous mechanisms known to generate oxidants, leakage of the superoxide anion and hydrogen peroxide from the mitochondrial electron transport chain are of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mitochondria
Share to Aging
Share to Antioxidants

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Mitochondrial

Share to Longevity

Share to Mammals

Share to Mutation

Share to Oxidative Phosphorylation

Source

Identifiers

PMID: 9928425
DOI: 10.1111/j.1749-6632.1998.tb09897.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial aging: open questions.PMID 9928425Read ↗

Reconsidering the Role of Mitochondria in AgingSemantic proximity Read ↗

Mitochondrial dysfunction in aging: Much progress but many unresolved questions.Semantic proximity Read ↗

The Mitochondrial Basis of Aging and Age-Related DisordersSemantic proximity Read ↗

Multiple Roles of Mitochondria in Aging ProcessesSemantic proximity Read ↗

Mitochondria and AgeingSemantic proximity Read ↗

Mitochondrial DNA mutations, oxidative stress, and aging.Semantic proximity Read ↗

Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging.Semantic proximity Read ↗

Mitochondria and aging.Semantic proximity Read ↗

Mitochondrial abnormalities in muscle and other aging cells: classification, causes, and effects.Semantic proximity Read ↗

Mitochondria and aging: innocent bystanders or guilty parties?Semantic proximity Read ↗

Mitochondria in organismal aging and degeneration.Semantic proximity Read ↗

Role of mitochondria in oxidative stress and ageing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.