Article
5-HT4 receptors: cloning and expression of new splice variants.
Annals of the New York Academy of Sciences - 15 Dec 1998
Claeysen S, Faye P, Sebben M, Taviaux S, Bockaert J, Dumuis A
Abstract excerpt
On the basis of differences in the potencies and intrinsic activity of 5-HT4 receptor agonists in different biological models it has been suggested that there is heterogeneity among 5-HT4 receptors. Here, we report the molecular cloning of several 5-HT4 receptor splice variants in mouse, rat, and...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Brain
- Chromosome Mapping
- Chromosomes, Human, Pair 5
- Cloning, Molecular
- Genetic Variation
- Humans
- Mice
- Molecular Sequence Data
- Rats
- Receptors, Serotonin
- Receptors, Serotonin, 5-HT4
- Recombinant Proteins
- Sequence Alignment
- Sequence Homology, Amino Acid