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Article

The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution.

Naunyn-Schmiedeberg's archives of pharmacology - 1 Jun 2001

Krobert K A, Bach T, Syversveen T, Kvingedal A M, Levy F O

Abstract excerpt

Serotonin (5-hydroxytryptamine, 5-HT) receptor pre-mRNA is alternatively spliced in human tissue to produce three splice variants, h5-HT7(a), h5-HT7(b) and h5-HT7(d), which differ only in their carboxyl terminal tails. Using membranes from transiently and stably transfected HEK293 cells expressing the three recombinant h5-HT7 splice variants we compared their pharmacological profiles and ability to activate...

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PMID: 11414657
DOI: 10.1007/s002100000369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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