Article
Structure of the human serotonin 5-HT4 receptor gene and cloning of a novel 5-HT4 splice variant.
Journal of neurochemistry - 1 Feb 2000
Bender E, Pindon A, van Oers I, Zhang Y B, Gommeren W, Verhasselt P, Jurzak M, Leysen J, Luyten W
Abstract excerpt
Several variants of the serotonin 5-HT4 receptor are known to be produced by alternative splicing. To survey the existence and usage of exons in humans, we cloned the human 5-HT4 gene. Based on sequence analysis seven C-terminal variants (a-g) and one internal splice variant (h) were found. We concentrated in this study on the functional characterization of the novel splice variant h, which leads to the insertion...
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