Article
POG1, a novel yeast gene, promotes recovery from pheromone arrest via the G1 cyclin CLN2.
Genetics - 1 Feb 1999
Leza M A, Elion E A
Abstract excerpt
In the absence of a successful mating, pheromone-arrested Saccharomyces cerevisiae cells reenter the mitotic cycle through a recovery process that involves downregulation of the mating mitogen-activated protein kinase (MAPK) cascade. We have isolated a novel gene, POG1, whose promotion of recovery parallels that of the MAPK phosphatase Msg5. POG1 confers alpha-factor resistance when overexpressed and enhances...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
