Article
Quantitative trait loci for estrogen-dependent pituitary tumor growth in the rat.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1997
Wendell D L, Gorski J
Abstract excerpt
Growth control is of fundamental importance to biology in general and of critical importance to cancer research in particular. Tumors develop when control of the normal growth process is lost. The rat pituitary is a model system for control of estrogen-dependent growth. Chronic estrogen treatment induces uncontrolled growth in the pituitaries of Fischer 344 (F344) rats, but not of Brown Norway (BN) rats. We have...
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