Increased expression of a hemimethylated oriC binding protein, SeqA, in an aphA mutant.

doi:10.1016/s0300-9084(99)80010-8

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Article

Increased expression of a hemimethylated oriC binding protein, SeqA, in an aphA mutant.

Biochimie - 1 Dec 1998

Kohiyama M, Bahloul A, Kern R, Meury J, Reshetnyak E, Malki A, Guha S

Abstract excerpt

In Escherichia coli, the origin of DNA replication, oriC, becomes transiently hemimethylated at the GATC sequences immediately after initiation of replication and this hemimethylated state is prolonged because of its sequestration by a fraction of outer membrane. This sequestration is dependent o...

Topics

Acid Phosphatase
Aminohydrolases
Bacterial Outer Membrane Proteins
Bacterial Proteins
Cloning, Molecular
DNA-Binding Proteins
Escherichia coli Proteins
Methylation
Mutation
Transcription Factors

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