Article
Prolonged upregulation of the expression of HLA class I antigens and costimulatory molecules on melanoma cells treated with 5-aza-2'-deoxycytidine (5-AZA-CdR).
Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 Jan 1999
Coral S, Sigalotti L, Gasparollo A, Cattarossi I, Visintin A, Cattelan A, Altomonte M, Maio M
Abstract excerpt
The immunogenic potential of melanoma cells and their recognition by the host's cytotoxic cells depends on the presence and on the level of expression of human leukocyte antigen (HLA) class I antigens, costimulatory molecules and melanoma-associated antigens (MAA), on neoplastic cells. In this st...
Topics
- Alleles
- Antigens, Neoplasm
- Azacitidine
- Blotting, Western
- CD58 Antigens
- Decitabine
- Flow Cytometry
- Histocompatibility Antigens Class I
- Humans
- Intercellular Adhesion Molecule-1
- Melanoma
- Melanoma-Specific Antigens
- Neoplasm Proteins