Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene.

The Journal of biological chemistry - 4 Oct 1996

Fan C Y, Pan J, Chu R, Lee D, Kluckman K D, Usuda N, Singh I, Yeldandi A V, Rao M S, Maeda N, Reddy J K

Abstract excerpt

Peroxisomal genetic disorders, such as Zellweger syndrome, are characterized by defects in one or more enzymes involved in the peroxisomal beta-oxidation of very long chain fatty acids and are associated with defective peroxisomal biogenesis. The biologic role of peroxisomal beta-oxidation system...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Homozygote
Share to Liver

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

Share to Mice, Inbred C57BL

Share to Mice, Mutant Strains

Share to Microscopy, Electron

Source

Identifiers

PMID: 8798738
DOI: 10.1074/jbc.271.40.24698

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-8798738-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene.PMID 8798738Read ↗

Peroxisomal and mitochondrial fatty acid beta-oxidation in mice nullizygous for both peroxisome proliferator-activated receptor alpha and peroxisomal fatty acyl-CoA oxidase. Genotype correlation with fatty liver phenotype.Semantic proximity Read ↗

Overexpression of peroxisome proliferator-activated receptor-alpha (PPARalpha)-regulated genes in liver in the absence of peroxisome proliferation in mice deficient in both L- and D-forms of enoyl-CoA hydratase/dehydrogenase enzymes of peroxisomal beta-oxidation system.Semantic proximity Read ↗

Progressive endoplasmic reticulum stress contributes to hepatocarcinogenesis in fatty acyl-CoA oxidase 1-deficient mice.Semantic proximity Read ↗

Longitudinal study of liver disease progression in the PEX1-Gly844Asp mouse model of mild Zellweger Spectrum DisorderSemantic proximity Read ↗

Hepatic dysfunction in peroxisomal disorders.Semantic proximity Read ↗

Human disorders of peroxisome metabolism and biogenesis.Semantic proximity Read ↗

Peroxisomal disorders.Semantic proximity Read ↗

Peroxisome biogenesis disorders.Semantic proximity Read ↗

A mouse model for X-linked adrenoleukodystrophy.Semantic proximity Read ↗

Decreased longevity and enhancement of age-dependent lesions in mice lacking the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha).Semantic proximity Read ↗

Peroxisomal disorders.Semantic proximity Read ↗

Disturbed Cholesterol Homeostasis in a Peroxisome-Deficient PEX2 Knockout Mouse ModelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.