JAK/STAT-deficient cell lines.

doi:10.1590/s0100-879x1998001100004

Article

JAK/STAT-deficient cell lines.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Nov 1998

Bonjardim C A

Abstract excerpt

Mutant cell lines B3 and B10, which are unresponsive to both interferon (IFN)-alpha and IFN-gamma, and line B9, which does not respond to IFN-gamma stimulation, are described. The mutants were submitted to fluorescence-activated cell sorting (FACS) from a cellular pool, which was obtained from th...

Topics

Cell Line
Cell Separation
Flow Cytometry
Interferons
Mutation
Protein-Tyrosine Kinases
Ribonucleases
Signal Transduction
Transcriptional Activation

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