Article
JAK/STAT-deficient cell lines.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Nov 1998
Bonjardim C A
Abstract excerpt
Mutant cell lines B3 and B10, which are unresponsive to both interferon (IFN)-alpha and IFN-gamma, and line B9, which does not respond to IFN-gamma stimulation, are described. The mutants were submitted to fluorescence-activated cell sorting (FACS) from a cellular pool, which was obtained from the parental cell line 2C4 after several rounds of mutagenesis. The unresponsiveness to IFN stimulation was observed both...
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