Interferon system in primary acute lymphocytic leukemia cells with or without deletions of the alpha-/beta-interferon genes.

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Article

Interferon system in primary acute lymphocytic leukemia cells with or without deletions of the alpha-/beta-interferon genes.

Blood - 15 Apr 1992

Grandér D, Heyman M, Bröndum-Nielsen K, Liu Y, Lundgren E, Söderhäll S, Einhorn S

Abstract excerpt

Various aspects of the interferon (IFN) system were studied in malignant cells from 37 unselected patients with acute lymphocytic leukemia (ALL). It was found that leukemic cells from two of 37 patients had a complete loss of alpha- and beta-IFN genes, whereas cells from four of 37 had lost one o...

Topics

2',5'-Oligoadenylate Synthetase
Adolescent
Adult
Alleles
Blotting, Southern
Burkitt Lymphoma
Cells, Cultured
Child, Preschool
Chromosome Deletion
DNA, Neoplasm
Humans
Infant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interferon Type I

Interferon-alpha

Interferon-beta

Karyotyping

Kinetics

Leukemia-Lymphoma, Adult T-Cell

Source

Open in PubMed

Identifiers

PMID: 1562733

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1562733-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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