UV-induced mutations and skin cancer: how important is the link?

doi:10.1016/s0027-5107(98)00172-9

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Article

UV-induced mutations and skin cancer: how important is the link?

Mutation research - 9 Nov 1998

Bridges B A

Abstract excerpt

Studies with patients having the inherited DNA repair disorders xeroderma pigmentosum (XP), Cockayne syndrome (CS), and sun-sensitive trichothiodystrophy (TTD) have shown that neither the defect in repair nor the consequent elevated frequency of sunlight-induced mutations in the skin is sufficien...

Topics

Animals
Cockayne Syndrome
DNA Repair
Hair
Humans
Mutation
Neoplasms, Radiation-Induced
Skin
Skin Neoplasms
Sunlight
Transcription, Genetic
Ultraviolet Rays
Xeroderma Pigmentosum

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