Sunlight-induced cancer: some new aspects and implications of the xeroderma pigmentosum model.

doi:10.1111/j.1365-2133.1990.tb16136.x

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Article

Sunlight-induced cancer: some new aspects and implications of the xeroderma pigmentosum model.

The British journal of dermatology - 1 Apr 1990

Lehmann A R, Bridges B A

Abstract excerpt

Symptoms of xeroderma pigmentosum, a hereditary disease characterized by accelerated light-induced ageing of the skin, are due to deficiencies in the repair of damaged DNA. Following UV irradiation a high incidence of thioguanine-resistant mutations have been observed, which may be a model for th...

Topics

DNA Damage
Humans
Killer Cells, Natural
Models, Biological
Mutation
Skin Neoplasms
Sunlight
Xeroderma Pigmentosum

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