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Article

Abnormal erythemal response and elevated T lymphocyte HRPT mutant frequency in Cockayne's syndrome.

The British journal of dermatology - 1 May 1991

Norris P G, Arlett C F, Cole J, Lehmann A R, Hawk J L

Abstract excerpt

In three children with Cockayne's syndrome (CS), skin exposed to ultraviolet radiation responded transiently either with erythematous papules or an exaggerated sunburn-like response, without chronic actinic damage. Irradiation monochromator tests demonstrated an abnormal delay or reduction in the threshold to ultraviolet (UVB) irradiation-induced erythema similar to that of xeroderma pigmentosum (XP). As with XP...

Topics

Child, Preschool
Cockayne Syndrome
Erythema
Female
Humans
Immunity, Cellular
Killer Cells, Natural
Mutation
Photosensitivity Disorders
T-Lymphocytes
Xeroderma Pigmentosum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2039722
DOI: 10.1111/j.1365-2133.1991.tb00625.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2039722-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Abnormal erythemal response and elevated T lymphocyte HRPT mutant frequency in Cockayne's syndrome.PMID 2039722Read ↗

Absence of skin cancer in the DNA repair-deficient disease Cockayne Syndrome (CS): A survey studySemantic proximity Read ↗

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Why Cockayne syndrome patients do not get cancer despite their DNA repair deficiency.Semantic proximity Read ↗

Two new XPD patients compound heterozygous for the same mutation demonstrate diverse clinical features.Semantic proximity Read ↗

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UVB radiation-induced cancer predisposition in Cockayne syndrome group A (Csa) mutant mice.Semantic proximity Read ↗

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Xeroderma pigmentosum and Cockayne syndrome: overlapping clinical and biochemical phenotypes.Semantic proximity Read ↗

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A UV-sensitive syndrome patient with a specific CSA mutation reveals separable roles for CSA in response to UV and oxidative DNA damage.Semantic proximity Read ↗

The relationship between benzo[a]pyrene-induced mutagenesis and carcinogenesis in repair-deficient Cockayne syndrome group B mice.Semantic proximity Read ↗

A novel DNA repair disorder with thrombocytopenia, nephrosis and features overlapping Cockayne syndrome.Semantic proximity Read ↗

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