Article
Analysis of mutations occurring at the human hprt locus.
Journal of molecular biology - 5 May 1993
Cariello N F, Skopek T R
Abstract excerpt
We have recently established a computerized database containing information on mutants at the human hypoxanthine guanine phosphoribosyl transferase (hprt) locus. The database contains sequence information on over 1000 mutants. We now present an analysis of the information in the database. 542 single base substitution mutants in the hprt coding region exist, and we have examined (1) the number of mutations and the...
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