Article
Structural and functional analysis of the protein products derived from mutant fur alleles in an endoprotease-deficient Chinese hamster ovary cell strain.
Somatic cell and molecular genetics - 1 Mar 1998
Sucic J F, Spence M J, Moehring T J
Abstract excerpt
The fur gene encodes the endoprotease, furin. We recently demonstrated mutations in both fur alleles in the mutant Chinese hamster ovary (CHO)-K1 strain, RPE.40, and hypothesized that these mutations were responsible for the endoprotease-deficient phenotype of these cells. We now present the structural and functional properties of three protein products derived from the mutant fur alleles. None of these protein...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
