Analysis of mutations in alleles of the fur gene from an endoprotease-deficient Chinese hamster ovary cell strain.

doi:10.1007/BF02255818

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Article

Analysis of mutations in alleles of the fur gene from an endoprotease-deficient Chinese hamster ovary cell strain.

Somatic cell and molecular genetics - 1 Jan 1995

Spence M J, Sucic J F, Foley B T, Moehring T J

Abstract excerpt

RPE.40 mutant cells differ from wild-type Chinese hamster ovary (CHO-K1) cells in their increased resistance to Pseudomonas exotoxin A and their inability to process the insulin proreceptor and certain viral envelope proproteins. Northern analysis revealed that RPE.40 cells maintained a substanti...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Blotting, Northern
CHO Cells
Cricetinae
DNA, Complementary
Female
Furin
Molecular Sequence Data
Point Mutation
RNA, Messenger
Sequence Alignment
Subtilisins

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