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Article

Mutagenesis of hepatitis E virus helicase motifs: effects on enzyme activity.

Virus research - 22 Jan 2014

Mhaindarkar Vaibhav, Sharma Kavyanjali, Lole Kavita S

Abstract excerpt

Hepatitis E virus (HEV), the causative agent of hepatitis E, is a non-enveloped RNA virus. The open reading frame 1 encoded non-structural polyprotein has putative domains for methyltransferase, cysteine protease, helicase and RNA-dependent RNA polymerase, however processing of this polyprotein is still uncertain. HEV helicase belongs to superfamily 1 and has all seven conserved motifs typical of the family....

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Identifiers

PMID: 24333153
DOI: 10.1016/j.virusres.2013.11.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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