Article
Implication of molecular analysis of HLA-A*02 subtyping for unrelated bone-marrow donor selection.
Bone marrow transplantation - 1 Dec 1998
Cecuk-Jelicić E, Grubić Z, Zunec R, Labar B, Kerhin-Brkljacić V, Kastelan A
Abstract excerpt
The HLA-A*02 allele is the most heterogeneous allele at HLA-A locus with 22 different subtypes so far identified. All of these subtype polymorphisms are located in alpha 1 and alpha 2 domains which are responsible for peptide biding and HLA restricted recognition by T-cell receptor. The aim of the present study was to determine the frequency of different HLA-A*02 alleles in 33 healthy unrelated Croatians....
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