Article
Mapping the Human Leukocyte Antigen Diversity among Croatian Regions: Implication in Transplantation.
Journal of immunology research - 1 Jan 2021
Grubic Zorana, Maskalan Marija, Stingl Jankovic Katarina, Burek Kamenaric Marija, Zunec Renata
Abstract excerpt
In the present study, HLA allele and haplotype frequencies were studied using the HLA data of 9277 Croatian unrelated individuals, typed using high-resolution methods for the HLA-A, -B, -C, and -DRB1 loci. The total numbers of observed alleles were 47 for HLA-A, 88 for HLA-B, 34 for HLA-C, and 53 for HLA-DRB1. HLA-A∗02:01 (29.5%), B∗51:01 (10.5%), C∗04:01 (15.8%), and DRB1∗16:01 (10.4%) were the most frequent...
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