Article
Determination of HLA-A, -B, and -DRB1 Allele and Haplotype Frequencies in the Croatian Population Based on a Family Study.
Archivum immunologiae et therapiae experimentalis - 1 Dec 2016
Grubic Zorana, Maskalan Marija, Svilicic Danijela, Stingl Jankovic Katarina, Zunec Renata
Abstract excerpt
In the present study, HLA allele and haplotype frequencies among Croatian families were investigated to evaluate valuable information about HLA genotypes and to compare them with data from the Croatian Bone Marrow Donor Registry (CBMDR). A total of 350 families which have been typed for the purpose of HSCT were included. All individuals were tested using PCR-SSO or PCR-SSP methods for HLA-A, -B, and -DRB1...
Topics
- Alleles
- Croatia
- Family Health
- Female
- Gene Frequency
- Genetics, Population
- HLA-A Antigens
- HLA-B Antigens
- HLA-DRB1 Chains
- Haplotypes
- Hematopoietic Stem Cell Transplantation
- Humans
- Male
- Parents
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Unrelated Donors