Article
Sexually dimorphic sterility phenotypes in Hoxa10-deficient mice.
Nature - 30 Mar 1995
Satokata I, Benson G, Maas R
Abstract excerpt
The Abdominal B (AbdB) genes constitute a distinct subfamily of homeobox genes that exhibit posterior domains of expression, including the genital imaginal disc in Drosophila and the developing urogenital system in vertebrates. We have mutated the AbdB gene Hoxa10 in mice. We report here that hom...
Topics
- Animals
- Cryptorchidism
- DNA-Binding Proteins
- Embryonic and Fetal Development
- Female
- Genes, Homeobox
- Homeobox A10 Proteins
- Homeodomain Proteins
- Homozygote
- Infertility, Male
- Lumbar Vertebrae
- Male
- Mesoderm
- Mice
- Mutagenesis
- Ovulation
- Phenotype
- Sex Characteristics