Article
Oligomerization of the 17-kDa peptide-binding domain of the molecular chaperone HSC70.
European journal of biochemistry - 1 Jan 1999
Fouchaq B, Benaroudj N, Ebel C, Ladjimi M M
Abstract excerpt
Crystallographic and biochemical studies have indicated that the peptide-binding site of the molecular chaperone HSC70 is located in a small subdomain comprising a beta-sheet motif followed by a helical region, and there is some evidence of the involvement of this site in oligomerization of the protein. To determine the structure of this subdomain in solution and examine its involvement in oligomerization of...
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