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Article

Uncoupling of peptide-stimulated ATPase and clathrin-uncoating activity in deletion mutant of hsc70.

The Journal of biological chemistry - 25 Feb 1994

Tsai M Y, Wang C

Abstract excerpt

The recombinant 60-kDa fragment of rat hsc70 has been overexpressed in Escherichia coli. The recombinant protein is not capable of disassembling clathrin from coated vesicles. However, the affinity for peptides and the peptide-stimulated ATPase activity of the intact protein are retained in the 60-kDa fragment. The dissociation constants of peptide P3a (the recognition sequence of clathrin light chain LCa by...

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PMID: 8119940

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Uncoupling of peptide-stimulated ATPase and clathrin-uncoating activity in deletion mutant of hsc70.PMID 8119940Read ↗

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