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Article

Three-dimensional structural studies on fragments of fibrinogen and fibrin.

Current opinion in structural biology - 1 Dec 1998

Doolittle R F, Spraggon G, Everse S J

Abstract excerpt

Fibrinogen is a 340 kDa glycoprotein found in the blood plasma of all vertebrates. It is transformed into a fibrin clot by the action of thrombin. Recent X-ray structures of core fragments of both fibrinogen and fibrin have revealed many details about this polymerization event. These include structures of a 30 kDa recombinant gammaC domain, an 86 kDa fragment D from human fibrinogen and a cross-linked double-D...

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Identifiers

PMID: 9914253
DOI: 10.1016/s0959-440x(98)80100-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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