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The embryonic origins of hematopoietic stem cells: a tale of hemangioblast and hemogenic endothelium

1 Nov 2005

Abstract excerpt

The developmental origin of hematopoietic stem cells has been for decades the subject of great interest. Once thought to emerge from the yolk sac, hematopoietic stem cells have now been shown to originate from the embryonic aorta. Increasing evidence suggests that hematopoietic stem cells are produced from an endothelial intermediate designated by the authors as hemangioblast or hemogenic endothelium. Recently,...

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PMID: 16480450
DOI: 10.1111/j.1600-0463.2005.apm_317.x

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