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Article

Evidence that two independent host genes influence the severity of tissue damage and susceptibility to acute pyelonephritis in murine systemic candidiasis.

Microbial pathogenesis - 1 Mar 1997

Ashman R B, Fulurija A, Papadimitriou J M

Abstract excerpt

Tissue damage in the kidney and brain after systemic infection with Candida albicans was examined in recombinant inbred strains (AKXL) derived from AKR and C57/L progenitors. Nine of the 15 strains showed mild (C57/L-like) tissue damage. Of the remainder, two strains developed lesions comparable to the AKR parental strain, whereas four exhibited a much more severe pattern of tissue damage. This was characterized...

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Identifiers

PMID: 9075221
DOI: 10.1006/mpat.1996.0102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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