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Article

Genetic control of susceptibility to Candida albicans in SM/J mice.

Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 2014

Radovanovic Irena, Leung Vicki, Iliescu Alexandra, Bongfen Silayuv E, Mullick Alaka, Langlais David, Gros Philippe

Abstract excerpt

In the immunocompromised host, invasive infection with the fungal pathogen Candida albicans is associated with high morbidity and mortality. Sporadic cases in otherwise normal individuals are rare, and they are thought to be associated with genetic predisposition. Using a mouse model of systemic infection with C. albicans, we identified the SM/J mouse strain as unusually susceptible to infection. Genetic linkage...

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Source

Identifiers

PMID: 24973457
DOI: 10.4049/jimmunol.1400783

Genes

CCL2
STAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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