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Article

Alterations of tumor suppressor gene p16INK4a in pancreatic ductal carcinoma.

BMC gastroenterology - 28 Jun 2005

Attri Jyotika, Srinivasan Radhika, Majumdar Siddhartha, Radotra Bishan Dass, Wig Jaidev

Abstract excerpt

BACKGROUND: Cell cycle inhibitor and tumor suppressor gene p16/MTS-1 has been reported to be altered in a variety of human tumors. The purpose of the study was to evaluate primary pancreatic ductal adenocarcinomas for potentially inactivating p16 alterations. METHODS: We investigated the status of p16 gene by polymerase chain reaction (PCR), nonradioisotopic single strand conformation polymorphism (SSCP), DNA...

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Share to Adenocarcinoma
Share to Carcinoma, Pancreatic Ductal
Share to Cyclin-Dependent Kinase Inhibitor p16

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Gene Silencing

Share to Genes, p16

Share to Polymorphism, Single-Stranded Conformational

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Source

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Identifiers

PMID: 15985168
DOI: 10.1186/1471-230X-5-22
PMCID: PMC1185532

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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