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Article

P16 hypermethylation contributes to the characterization of gene inactivation profiles in primary gastric cancer.

Oncology reports - 1 Jan 2000

Ficorella Corrado, Cannita Katia, Ricevuto Enrico, Toniato Elena, Fusco Carlo, Sinopoli Nuntia Teresa, De Galitiis Federica, Di Rocco Zorika Christiana, Porzio G, Frati Luigi, Gulino Alberto, Martinotti Stefano, Marchetti Paolo

Abstract excerpt

The objective of this study was to investigate the contribution of p16 inactivation in gastric cancer and to compare it with p53. A cohort of 34 primary GCs were analyzed for p16 mutations and transcriptional silencing of the gene due to hypermethylation of the promoter. SSCP analysis and direct...

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Identifiers

PMID: 12469165

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12469165-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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