The proximal tubule phenotype and its disruption in acute renal failure and polycystic kidney disease.

Abstract excerpt

In light of recent developments in the fields of genetics, molecular, cell and developmental biology, the kidney is receiving increasing attention as a model system for organ development and human diseases. Gene disruption experiments have provided evidence for the essential role of a number of p...

Topics

• Acute Kidney Injury
• Animals
• Disease Models, Animal
• Genes, Regulator
• Humans
• Ischemia
• Kidney Tubules, Proximal
• Mice
• Phenotype
• Polycystic Kidney Diseases