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Article

Genetic and developmental basis for urinary tract obstruction.

Pediatric nephrology (Berlin, Germany) - 1 Sept 2009

Chen Feng

Abstract excerpt

Urinary tract obstruction results in obstructive nephropathy and uropathy. It is the most frequent cause of renal failure in infants and children. In the past two decades studies of transgenic models and humans have greatly enhanced our understanding of the genetic factors and developmental processes important in urinary tract obstruction. The emerging picture is that development of the urinary tract requires...

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Identifiers

PMID: 19085015
DOI: 10.1007/s00467-008-1072-y
PMCID: PMC2844875

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