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Article

A Human Minor Histocompatibility Antigen Specific for B Cell Acute Lymphoblastic Leukemia

18 Jan 1999

Abstract excerpt

Human minor histocompatibility antigens (mHags) play an important role in the induction of cytotoxic T lymphocyte (CTL) reactivity against leukemia after human histocompatibility leukocyte antigen (HLA)-identical allogeneic bone marrow transplantation (BMT). As most mHags are not leukemia specific but are also expressed by normal tissues, antileukemia reactivity is often associated with life-threatening...

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PMID: 9892612
DOI: 10.1084/jem.189.2.301

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