Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expanding the immunotherapeutic potential of minor histocompatibility antigens.

The Journal of clinical investigation - 1 Dec 2005

Spierings Eric, Goulmy Els

Abstract excerpt

Minor histocompatibility antigens (mHAgs) selectively expressed by cells or cell subsets of the hematopoietic system are targets of the T cell-mediated graft-versus-leukemia response that develops following allogeneic hematopoietic stem cell transplantation (HSCT) for the treatment of hematological malignancies. This observation has served as the rationale for utilizing mHAg-specific immunotherapy for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Transplantation
Share to HLA-B7 Antigen
Share to Immunotherapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Minor Histocompatibility Antigens

Share to T-Lymphocytes, Cytotoxic

Share to Tissue Distribution

Share to Transplantation, Homologous

Source

Open in PubMed Open full text

Identifiers

PMID: 16322786
DOI: 10.1172/JCI27094
PMCID: PMC1297265

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expanding the immunotherapeutic potential of minor histocompatibility antigens.PMID 16322786Read ↗

Exploiting T cells specific for human minor histocompatibility antigens for therapy of leukemiaSemantic proximity Read ↗

Minor Histocompatibility AntigensSemantic proximity Read ↗

Associations of Minor Histocompatibility Antigens with Clinical Outcomes Following Allogeneic Hematopoietic Cell TransplantationSemantic proximity Read ↗

Leukemia-associated minor histocompatibility antigen discovery using T-cell clones isolated by in vitro stimulation of naive CD8+ T cells.Semantic proximity Read ↗

Immunotherapy of cancer through targeting of minor histocompatibility antigensSemantic proximity Read ↗

Cytotoxic T-lymphocyte-defined human minor histocompatibility antigens with a restricted tissue distribution.Semantic proximity Read ↗

Shared Graft Versus Leukemia Minor Histocompatibility Antigens in DISCOVeRY-BMTSemantic proximity Read ↗

Molecular typing methods for minor histocompatibility antigens.Semantic proximity Read ↗

Common minor histocompatibility antigen discovery based upon patient clinical outcomes and genomic data.Semantic proximity Read ↗

Computational modeling and confirmation of leukemia-associated minor histocompatibility antigensSemantic proximity Read ↗

Identification of 4 new HLA-DR-restricted minor histocompatibility antigens as hematopoietic targets in antitumor immunity.Semantic proximity Read ↗

High-throughput characterization of 10 new minor histocompatibility antigens by whole genome association scanning.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.