Article
HTLV-1 bZIP factor-specific CD4 T cell responses in adult T cell leukemia/lymphoma patients after allogeneic hematopoietic stem cell transplantation.
Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 2014
Narita Tomoko, Ishida Takashi, Masaki Ayako, Suzuki Susumu, Ito Asahi, Mori Fumiko, Yamada Tomiko, Ri Masaki, Kusumoto Shigeru, Komatsu Hirokazu, Miyazaki Yasuhiko, Takatsuka Yoshifusa, Utsunomiya Atae, Niimi Akio, Iida Shinsuke, Ueda Ryuzo
Abstract excerpt
We document human T lymphotropic virus type 1 (HTLV-1) bZIP factor (HBZ)-specific CD4 T cell responses in an adult T cell leukemia/lymphoma (ATL) patient after allogeneic hematopoietic stem cell transplantation (HCT) and identified a novel HLA-DRB1*15:01-restricted HBZ-derived naturally presented minimum epitope sequence, RRRAEKKAADVA (HBZ114-125). This peptide was also presented on HLA-DRB1*15:02, recognized by...
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