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Article

Allele-specific suppression of ColE1 high-copy-number mutants by a rpoB mutation of Escherichia coli.

Plasmid - 1 Jan 1999

Yang Y L, Polisky B

Abstract excerpt

We have isolated spontaneous rifampicin-resistant mutants from Escherichia coli that showed allele-specific suppression of the copy-number phenotype of ColE1 high-copy-number mutants in vivo. The key step in the regulatory circuitry of the initiation of ColE1 DNA replication is the formation of the persistent hybrid between the primer RNA and the DNA template around the replication origin. Three host-encoded...

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Identifiers

PMID: 9887306
DOI: 10.1006/plas.1998.1378

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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