Cytosine methylation and mammalian development.

doi:10.1101/gad.13.1.26

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Article

Cytosine methylation and mammalian development.

Genes & development - 1 Jan 1999

Walsh C P, Bestor T H

Abstract excerpt

Programmed methylation and demethylation of regulatory sequences has been proposed to play a central role in vertebrate development. We report here that the methylation status of the 5' regions of a panel of tissue-specific genes could not be correlated with expression in tissues of fetal and new...

Topics

Alleles
Animals
CpG Islands
Cytosine
DNA (Cytosine-5-)-Methyltransferases
DNA Methylation
Embryo, Mammalian
Gene Expression Regulation, Developmental
Mammals
Mice
Promoter Regions, Genetic
RNA, Messenger
Regulatory Sequences, Nucleic Acid
Transcriptional Activation

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