Article
Cytosine methylation and mammalian development.
Genes & development - 1 Jan 1999
Walsh C P, Bestor T H
Abstract excerpt
Programmed methylation and demethylation of regulatory sequences has been proposed to play a central role in vertebrate development. We report here that the methylation status of the 5' regions of a panel of tissue-specific genes could not be correlated with expression in tissues of fetal and newborn mice. Genes reported to be regulated by reversible methylation were not expressed ectopically or precociously in...
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