Article
DNA methylation and epigenetic inheritance.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 30 Jan 1990
Holliday R
Abstract excerpt
Classical genetics has revealed the mechanisms for the transmission of genes from generation to generation, but the strategy of the genes in unfolding the developmental programme remains obscure. Epigenetics comprises the study of the mechanisms that impart temporal and spatial control on the activities of all those genes required for the development of a complex organism from the zygote to the adult. Epigenetic...
Topics
- Aging
- Animals
- Cells, Cultured
- DNA
- Embryonic and Fetal Development
- Genetics
- Methylation
- Models, Genetic
- Mutation
- Phenotype