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Article

Domains of the Human Androgen Receptor Involved in Steroid Binding, Transcriptional Activation, and Subcellular Localization

1 Oct 1991

Abstract excerpt

A series of human androgen receptor (AR) deletion mutants was constructed to study the relationship between the structural domains and their different functions in the AR protein. Human AR mutants were expressed in COS-1 and HeLa cells to investigate hormone binding, transcriptional activation, and subcellular localization. The wild-type human AR (AR 1–910) was expressed as a 110- to 112-kDa doublet, as revealed...

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Identifiers

PMID: 1775129
DOI: 10.1210/mend-5-10-1396

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Source receipt: pubmed, retrieved 7 Sept 2026.

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